65th Annual Meeting and ToxExpo of the Society of Toxicology (SOT)
The 65th Annual SOT meeting is being held on 22nd – 25th March 2026 in San Diego, CA, USA.
The annual SOT meeting brings together around 5000 toxicologists and ecotoxicologists to share the latest developments in the field, including non-animal safety assessment. Unilever SERS scientists have co-authored ten oral and poster presentations this year – details below:
Sunday, 22nd March
1:00 - 5:00 pm - Continuing Education Course:
PM07- Evolution of OECD GL 497: Integration of NAMs for Skin Sensitisation Hazard and Point of Departure for Application in Risk Assessment. Chairs: Emily Reinke (US NIH) & Matthew Dent (Unilever)
Presentation – Matthew Dent (Unilever): Applying NAM-Derived Points of Departure (PoD) in Risk Assessment and Demonstration and Training of Tools for Estimating a PoD.
Monday, 23rd March
12:10 pm - 1:40 pm - Symposium Session:
Human and Ecological Risk Assessment: Has the Time Come for Greater Integration of Approaches?
Chairs: Lauren Brown (ToxStrategies LLC) & Bruno Campos (Unilever)
Presentation - Bruno Campos (Unilever): Case Study-Led Evaluation of an Integrated Human Health – Environmental Next Generation Risk Assessment (NGRA) Framework
9:15 - 10:15 am - International Collaboration on Cosmetics Safety Exhibitor Hosted Session:
Use of Next Generation Risk Assessment to Evaluate the Human Safety of Sunscreen Active Ingredients
Presentation – Matt Dent (Unilever): A Next Generation Risk Assessment Case Study on Oxybenzone
3:15 - 4:15 pm - Toxys Exhibitor Hosted Session:
NAMs and their (Regulatory) Applications in Safety Testing
Panel Discussion – DART and the Steps Needed to Move Towards In Vitro Strategies: Giel Hendrixks (Toxys), Pragati Coder (Charles River), Matt Dent (Unilever), Robert Landsiedel (BASF).
Tuesday, 24th March
1:00 pm - 2:30 pm - Workshop Session:
Integrating In Vitro Data and PBK Modelling for Exposure-Led Risk Assessment
Presentation – Ans Punt (Unilever): Building Confidence in Bottom-Up PBK Model Development for NGRA Without Support of In Vivo Data
Poster Presentations:
1) Poster Board Number: D289 - Human Induced Pluripotent Stem Cell (hiPSCs)-Derived Osteoblasts for In Vitro Assessment of Skeletal malformation.
Authors: P. van Rossum1, J. Horcas-Nieto1, G. Hendriks1, A. Jamalpoor1, and K. Wolton2.
1Toxys; 2SERS, Unilever.
2) Poster Board Number: G516 - Quantitative Estimates of Toxicodynamic Variability for New Approach Methodologies Based Systemic Safety Toolbox Using a Population-Based Human In Vitro Model.
Authors: I. F. Alshammari1, L. C. Ford1, H. D. Tsai1, H. Lin1, C. K. Negi1, A. N. Dickey2, F. A. Wright2, A. M. Middleton3, M. T. Baltazar3, J. Reynolds3, S. Cable3, A. Punt3, W. A. Chiu1, and I. Rusyn1.
1Texas A&M University, College Station; 2North Carolina State University; 3SERS, Unilever.
3) Poster Board Number: G541 - Application of a Human Reporter-Based Live-Cell Imaging Platform for Detection of Mitochondrial Toxicity.
Authors: T. Meijer1, B. Tangil1, B. ter Braak1, E. de Tombe1, S. Scott2, A. Wood2, and G. Hendriks1.
1Toxys; 2SERS, Unilever.
4) Poster Board Number: J662 - Evaluating Chemical and Clinical Spaces: The Bifunctional Reactivity of Respiratory Sensitizers in Comparison to Skin Sensitizers and Non-Sensitizing Irritants.
Authors: N. Sadekar1, J. Muldoon1, D. Botelho1, A. M. Bowden2, C. Ryan3, and F. Gerberick4.
1Research Institute for Fragrance Materials (RIFM); 2SERS, Unilever; 3ToxTech Solutions; 4GF3 Consultancy.
5) Poster Board Number: J636 - Exploring the Use of Cell Painting and Transcriptomics in a Battery of Human Cell Lines for Bioactivity-Based Chemical Prioritization.
Authors: A. Jurgelewicz1,2, C. M. Willis1, F. R. Harris1,2, G. Byrd1,2, D. E. Haggard1, J. L. Bundy1, L. J. Everett1, A. Middleton3, S. Cable3, B. A. Wetmore1, and J. A. Harrill1.
1U.S. Environmental Protection Agency (EPA); 2 Oak Ridge Institute for Science and Education (ORISE); 3 SERS, Unilever.