Lessons from toxicology: Developing a 21st-Century Paradigm for Medical Research1 November 2015Langley G, Austin CP, Balapure AK, Birnbaum LS, Bucher JR, Fentem J, Fitzpatrick CS, Fowle JR, Kavlock RJ, Kitano H, Lidbury BA, Muotri AR, Peng S-Q, Sakharov D, Seidle T, Trez T, Tonevitsky A, van de Stolpe A, Whelan M, Willett C (2015). Lessons from toxicology: Developing a...Download the publication
Adverse Outcome Pathways for Regulatory Applications: examination of four case studies with different degrees of completeness and scientific confidence20 October 2015Perkins EJ , Antczak P, Burgoon L, Falciani F, Garcia-Reyero N, Gutsell S, Hodges G, Kienzler A, Knaper D, McBride M, Willett C (2015). Adverse Outcome Pathways for Regulatory Applications: examination of four case studies with different degrees of completeness and scientific...Download the publication
A compilation of life cycle studies for six household detergent product categories in Europe: the basis for product-specific A.I.S.E. Charter Advanced Sustainability Profiles5 October 2015Golsteijn L, Menkveld R, King H, Schneider C, Schowanek D, Nissen S (2015) Environmental Sciences Europe, 27(23).Download the publication (Opens in a pop-up window )
Towards a non-animal risk assessment for anti-androgenic effects in humans1 October 2015Dent MP, Carmichael PL, Jones KC, Martin FL (2015). Towards a non-animal risk assessment for anti-androgenic effects in humans. Environment International, 94-106Download the publication
Adaptive Posttranslational Control in Cellular Stress Response Pathways and its Relationship to Toxicity Testing and Safety Assessment23 September 2015Zhang Q, Bhattacharya S, Pi J, Clewell RA, Carmichael PL, Andersen ME (2015). Adaptive Posttranslational Control in Cellular Stress Response Pathways and its Relationship to Toxicity Testing and Safety Assessment. Toxicological Sciences, 147(2) 2015, 302-316Download the publication
Glutathione metabolism in the HaCaT cell line as a model for the detoxification of the model sensitisers 2,4-dinitrohalobenzenes in human skin19 August 2015Jacquoilleot S, Sheffield D, Olayanju A, Sison-Young R, Kitteringham NR, Naisbitt DJ, Aleksic M (2015). Glutathione metabolism in the HaCaT cell line as a model for the detoxification of the model sensitisers 2,4-dinitrohalobenzenes in human skin. Toxicology Letters, 237, 11-20Download the publication
A new approach to modeling the sediment retention service (InVEST 3.0): Case study of the Cape Fear catchment, North Carolina, USA15 August 2015Hamel P, Chaplin-Kramer P, Sim S, Mueller C (2015) Science of the Total Environment, 524-525, 166-177.Download the publication (Opens in a pop-up window )
It is time to develop ecological threshold of toxicological concern to assist environmental hazard assessment25 June 2015Belanger SE, Sanderson H, Embry MR, Coady K, DeZwart D, Farr BA, Gutsell S, Halder M, Sternberg R, Wilson P (2015). It is time to develop ecological threshold of toxicological concern to assist environmental hazard assessment. Environmental Toxicology and Chemistry, 34, 2864-69Download the publication
Spatial patterns of agricultural expansion determine impacts on biodiversity and carbon storage15 June 2015Chaplin-Kramer R, Sharp RP, Mandle L, Sim S, Johnson J, Butnar I, Milà i Canals L, Eichelberger BA, Ramler I, Mueller C, McLachlan N, Yousefi A, King H, Kareiva PM (2015) Proceedings of the National Academy of Sciences (PNAS) , 112(24), 7402-07.Download the publication (Opens in a pop-up window )
Implementing Toxicity Testing in the 21st Century (TT21C): making safety decisions using toxicity pathways, and progress in a prototype risk assessment5 June 2015Adeleye Y, Andersen M, Clewell R, Davies M, Dent M, Edwards S, Fowler P, Malcomber S, Nicol B, Scott A, Scott S, Sun B, Westmoreland C, White A, Zhang Q, Carmichael PL (2014). Implementing Toxicity Testing in the 21st Century (TT21C): making safety decisions using toxicity...Download the publication
Dose metric considerations for in vitro assays to improve quantitative in vitro–in vivo dose extrapolations5 June 2015Groothuis FA, Heringa MB, Nicol B, Hermens JL, Blaauboer BJ, Kramer NI (2014). Dose metric considerations for in vitro assays to improve quantitative in vitro–in vivo dose extrapolations. Toxicology, 332, 30-40Download the publication
Analysis of water use impact assessment methods (part B): applicability for waterfootprintingand decision making with a laundry case study4 March 2015Boulay A-M, Bayart J-B, Bulle C, Franceschini H, Motoshita M, Muñoz I, Pfister S, Margni M (2015). Analysis of water use impact assessment methods (part B): applicability for water footprinting and decision making with a laundry case study. International Journal of Life Cycle...Download the publication